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Limitations of meta analyses are
2019-06-14

Limitations of meta-analyses are often based on the strength of the data available. Only 26% of the eligible studies were judged to be at low risk of overall bias in this analysis. Other studies may have been at low risk for bias but failed to report information necessary for this determination. All
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What would mitigation strategies to
2019-06-14

What would mitigation strategies to deal with future pandemic risks of zoonotic disease look like? Analyses of emerging disease trends during the past six decades have shown that Ebola fits the dopamine antagonist drugs pattern. This pattern involves zoonotic spillover from wildlife or livestock dri
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El proceso hist rico de conformaci n del
2019-06-14

El proceso histórico de conformación del Estado en Chile, su momento constitutivo en el siglo xix es precisamente la invasión del Estado liberal chileno a territorio de los pueblos originarios; desposesión que disocia la comunidad cultural mapuche de la soberanía territorial que hasta ese momento ha
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De manera puntual ambos gobiernos dejaron sentadas sus posic
2019-06-14

De manera puntual, ambos gobiernos dejaron sentadas sus posiciones ante el nuevo proceso bilateral para normalizar sus relaciones. En su alocución del 17 de diciembre de 2014, el general Raúl Castro destacó, entre otras cosas, que desde su elección como presidente de los consejos de Estado y de Mini
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In a letter to the editor
2019-06-14

In a letter to the editor of , Dasanu reported the case of a 55-yr-old male diagnosed with t(11;14)+ IgG-lambda MM, who presented with enlarged lymph nodes six years later. Biopsy was consistent with CD5-negative MCL. In 1999, Yamaguchi conducted clonal relationship analysis on myeloma and lymphoma
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br Results There were patients younger than years of age
2019-06-13

Results There were 81 patients younger than 50 years of age who received 12 cores TRUSP biopsy at TPEVGH from January 2008 to December 2013. Four patients who received TRUSP biopsy for abnormal DRE or prostate sonography findings were excluded for PSA RVX-208 group. There was no significant diffe
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br Methods br Results br Discussion
2019-06-13

Methods Results Discussion Conclusions Conflict of interest statement Introduction The origin of a nonsustained ventricular tachycardia (NSVT) can usually be estimated with the 12-lead electrocardiogram (ECG) [1–3]; however, anatomical abnormalities sometimes make it difficult to c
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br Conflict of interest br Authors contributions
2019-06-13

Conflict of interest Authors’ contributions Acknowledgements Introduction Aromatase-Inhibitors (AIs) are commonly used in the treatment of post-menopausal women with a history of hormone receptor-positive breast carcinoma, and have been shown to decrease bone mineral density (BMD) and in
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br Primary biliary cholangitis Primary biliary cholangitis P
2019-06-13

Primary biliary cholangitis Primary biliary cholangitis (PBC), previously known as primary biliary cirrhosis, is another rare but devastating immune-mediated cholangiopathy. Similar to PSC, PBC is characterized by portal inflammation leading to fibrosis and eventually cirrhosis. Distinct from PSC
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br Alegato y ret rica de la violencia
2019-06-13

Alegato y retórica de la violencia en la Brevíssima relación de la destruyción de las Indias En el año 1552 fray Bartolomé de las Casas, en Sevilla, se ocupa de dar tak1 kinase la imprenta ocho de sus principales escritos, entre ellos la Brevíssima relación, compuesta diez años antes: “Y pareciól
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Esto es visible no s lo en las notas necrol
2019-06-13

Esto es visible no sólo en las notas necrológicas, sino también en los discursos que homenajean epigallocatechin gallate alguien en ocasión de su retiro o jubilación. En ellos encontramos rasgos comunes con las notas necrológicas, sobre todo en la idea de una herencia que deja el que se va, y que co
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Desde su conceptuaci n inicial en por
2019-06-13

Desde su conceptuación inicial en 1968, por Gustavo Gutiérrez Merino —considerado “padre” y uno de los más trascendentes exponentes de esta corriente— la tl surgió como una reflexión posterior kinesin 5 un primer momento, consistente en la realidad misma de diversos sectores del pueblo latinoamerica
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In addition further study is required to evaluate
2019-06-13

In addition, further study is required to evaluate whether identified mutations influence post-translational modifications because they are important mechanism of transcription factors for regulating normal and leukemic hematopoiesis. Authors\' contributions Conflict of interest Acknowledgm
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Idelalisib demonstrates a dual mechanism of action by
2019-06-13

Idelalisib demonstrates a dual mechanism of action by inhibiting pro-survival signalling pathways [6], and, like other kinase inhibitors, leads to re-localisation of tumour D609 by blocking ingress into and promoting egress out of the lymph node into the blood. Release from the protective lymph envi
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A number of studies have
2019-06-12

A number of studies have shown that zoledronic equol has the ability to potentiate effects of anti-tumor agents such as doxorubicin [21] or everolimus [22]. In a recent paper the combination of chemotherapy with a single infusion of 4mg zoledronic acid in patients with breast cancer was shown to re
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