• br Future perspectives Identification of

  2019-05-04

  

  Future perspectives Identification of LOX as a modulator of the ECM to form pre-metastatic niches and subsequently bone metastasis arose as we were investigating the hypoxia tumour secretome using existing patient cohort data and cutting edge proteomics. Although condoned by some researchers as “

• In contrast to adults PBL

  2019-05-04

  

  In order WP1130 to adults, PBL in children is regarded as a clinical entity that is distinct from its adult counterpart. Like many other pediatric malignancies, PBL is considered a systemic disease in children. In small retrospective studies, PBL in children is characterized by rapid progression, a

• However it should be noted that

  2019-05-04

  

  However, it should be noted that large proportion of patients develop at least one SRE after BTAs orexin antagonist (74/155, 48%) appearing to be in keeping with the results of randomised BTA trials [3–6]. Indeed, for those patients who had not had an SRE prior to commencing a BTA, their risk of su

• Heat shock facilitates the folding of various proteins as

  2019-05-04

  

  Heat shock facilitates the folding of various proteins as mediated by the HSP family and can stabilize mutant proteins. HS has been reported to facilitate maturation of WT-HERG as well as mutant HERG by activating the HSF family [15]. HSF-1, 2, and 4 were reported to be expressed in humans. HSF-1 is

• Paraguay es puntual en la redacci n

  2019-05-04

  

  Paraguay es puntual en la redacción del Artículo 8 de su Constitución Nacional cuando dice que “Las actividades susceptibles de producir alteración ambiental serán reguladas por la ley. Asimismo, ésta podrá restringir o prohibir aquéllas que califique peligrosas”. Describe allí las actividades que p

• br Implementation of a programme called the the

  2019-05-04

  

  Implementation of a programme called the , the key component of the UNICEF/WHO Baby-Friendly Hospital Initiative (BFHI) increases exclusive breastfeeding at 3 months, any breastfeeding at 12 months, and reduces diarrhoeal disease. These outcomes were shown in a cluster-randomised study of 31 hospi

• De hecho la desordenada colecci n de los

  2019-05-04

  

  De hecho, la desordenada colección de los datos etnográficos se encuentra varias veces en conflicto con la propuesta de un proyecto sistemático que el fraile busca plantear, sin éxito, en el exordio de su obra. En las primeras páginas de la Relación, Pané esboza los confines de un modelo hermenéutic

• Si bien en Argentina la democracia

  2019-05-04

  

  Si bien en Argentina la democracia se alcanzó por el colapso de la dictadura, la guerra de Malvinas, la misma estaba planifi en las “Bases para la Intervención de las Fuerzas Armadas en el Proceso Nacional”. En este documento se indicaba que el proceso se desarrollaría mediante la ejecución de tres

• VE-822 Uma pena mas tudo n o passou

  2019-05-04

  

  Uma pena, mas tudo não passou de uma estratégia de venda, uma reunião de escritores que ficou somente na mediação do editor. Estratégia, aliás cada vez mais usada desde VE-822 tão comentada entrada da literatura brasileira no mercado internacional motivada principalemente pela retomada dos projetos

• br Case report A year

  2019-05-04

  

  Case report A 73 year-old man was diagnosed with chronic lymphocytic lymphoma (CLL) in December 2009, where he presented with a servical mass at another state hospital. He was treated with 6 cycles of cyclophosphamide, vincristine and prednisone (CVP). On follow-up he received 6 cycles of fludara

• Education is part of the foundation

  2019-05-04

  

  Education is part of the foundation for a successful ASP. A well-designed educational program provides prescribers with updated knowledge on antimicrobial use, drug resistance, and infectious disease management. Educational interventions have been shown to improve prescribing competency, change pre

• Introduction Acute acalculous cholecystitis ACC is defined a

  2019-04-30

  

  Introduction Acute acalculous cholecystitis (ACC) is defined as an acute necroinflammatory disease of the gallbladder in the absence of cholelithiasis and has a multifactorial pathogenesis [1]. ACC has very rarely been described in patients undergoing myelosuppressive chemotherapy for acute myelobl

• Our group then carried out

  2019-04-30

  

  Our group then carried out a study to determine the substrate sites and arrhythmogenic mechanisms of the BrS [29]. We found that all our BrS patients had abnormal low voltage, fractionated late potentials exclusively clustering in the anterior aspect of the RVOT epicardium and not seen anywhere else

• br We recently reported associations between maternal age

  2019-04-30

  

  We recently reported associations between maternal age at childbirth and outcomes in the offspring, using data from five birth cohorts (COHORTS collaboration) in low-income and middle-income countries (LMICs), in . Young maternal age ( Antimicrobial resistance is recognised as a serious global he

• br In its July editorial drew attention to the ethical

  2019-04-30

  

  In its July editorial, drew attention to the ethical challenges posed by the Zika casein kinase 2 inhibitor outbreak. The Regional Program on Bioethics at the Pan American Health Organization (PAHO) arranged an ethics consultation, funded by the Wellcome Trust, to provide ethically sound guidanc

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