• Data for each assessment point are expressed

  2019-04-15

  

  Data for each assessment point are expressed as the mean value plus standard deviation. One tailed paired t-tests were performed to analyze the effects of ibandronate treatment. Significance level was set at p Results The study included 33 patients with a variety of different primary tumors (Table

• In an effort to determine whether

  2019-04-15

  

  In an effort to determine whether the primary tumour might be responsible for “fertilising” the bone “soil” ready for the cancer “seed”, we recently found that a hypoxic gene signature, and more specifically the secreted enzyme lysyl oxidase (LOX) was closely associated with bone metastasis, specifi

• In addition to CAF in

  2019-04-15

  

  In addition to CAF in the primary tumour microenvironment, it is tempting to speculate that fibroblasts within the bone itself may play a role in the establishment of metastatic deposits. Fibroblasts form a major component of the bone marrow stroma and regulate haematopoiesis by secreting a range of

• br Introduction Atrial fibrillation AF

  2019-04-15

  

  Introduction Atrial fibrillation (AF) is the most clinically prevalent tachyarrhythmia [1,2]. AF is a potential risk factor for stroke, and AF-associated strokes are often severe, resulting in disability or death [3–6]. Anticoagulant therapy with the vitamin K antagonist warfarin reduces the risk

• br Genetic basis for atrial

  2019-04-15

  

  Genetic basis for atrial standstill Genetic basis of conduction block Genes involved in cardiac development and bradycardia Development of the CCS is a complex biological process with the potential to be wrought with problems. Several transcription factors, including homeodomain proteins an

• LQT can have numerous clinical manifestations

  2019-04-15

  

  LQT1 can have numerous clinical manifestations, ranging from no symptoms to sudden cardiac death, which reflects the heterogeneity in channel dysfunction. Mutation type, location, and even a patient׳s ethnic background, age, and gender are critical factors that affect the pathophysiology of the dise

• The most compelling apparent evidence in support of

  2019-04-15

  

  The most compelling apparent evidence in support of the depolarization hypothesis derives from the seminal studies of Nademanee et al. [129]. showing that radiofrequency ablation (RFA) of epicardial sites displaying late potentials and fractionated bipolar electrograms in the RVOT of patients with B

• The participants discussed several overarching

  2019-04-15

  

  The participants discussed several overarching themes, concluding that research is too often separate from implementation. A crucial gap remains between the development of efficacious health interventions and their optimum delivery in real-life settings. This gap is particularly true in many low-inc

• En M xico el folclor nacionalista de los siglos xix

  2019-04-15

  

  En México, el folclor nacionalista de los siglos xix y xx matizó la tipificada creencia cultural de la “convivencia natural” del mexicano con la muerte para explicar y sobrellevar, incluso de manera socarrona, los estragos económicos y sociales del destino mexicano. Elsa Malvido, en este sentido, en

• La fotograf a reforz el

  2019-04-15

  

  La fotografía reforzó EPZ-6438 el carácter militarista del pgt-pc. El ajusticiamiento de Zepeda Martínez perdió su fuerza política al carecer de los mecanismos de propaganda que acompañan una acción de este tipo. Si bien los recursos gráficos explotados por el periodismo difundieron la muerte del có

• br Case report A year old

  2019-04-15

  

  Case report A 73 year-old man was diagnosed with chronic lymphocytic lymphoma (CLL) in December 2009, where he presented with a servical mass at another state hospital. He was treated with 6 cycles of cyclophosphamide, vincristine and prednisone (CVP). On follow-up he received 6 cycles of fludara

• The exhibited efficacies of bone targeting

  2019-04-15

  

  The exhibited efficacies of bone targeting treatments, in phase III clinical trials, suggest significant progress in delaying skeletal-related events, with improvements having been seen in the direct comparisons between generations of drugs. These findings also lend clear support to the utility of b

• Expansion of access to HIV treatment is

  2019-04-11

  

  Expansion of access to HIV treatment is a global priority. In July, 2013, UNAIDS, in collaboration with WHO, the Global Fund to fight AIDS, Tuberculosis and Malaria, and the US President\'s Emergency Plan for AIDS Relief (PEPFAR) jointly issued which advocates for a worldwide treatment target of 15

• Una recopilaci n impresa del trabajo

  2019-04-11

  

  Una recopilación impresa del trabajo que realizó con su cámara, desde 1980 hasta 1986, fue publicado con el título: Guatemala: Eternal Spring, Eternal Tyranny en 1988. En 2010 reeditó el libro en español, el cual se difundió ampliamente en Guatemala como parte del proceso de recuperación histórica.

• Si bien ambas variables han tenido mal desempe

  2018-11-15

  

  Si bien ambas variables han tenido mal desempeño en las dos o tres décadas recientes, la evolución de la productividad laboral y la del salario mínimo real en México no están estrechamente correlacionadas, y más bien son contrastantes. En efecto, en el ámbito regional, México lleva años destacando p

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