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The fact that the in vitro induction
2018-11-14
The fact that the in vitro induction of osteogenic differentiation leads to sarcoma development from sarcoma iPSCs in concert with EWS-FLI1 expression indicates that these sarcomas arise from osteogenic progenitor cells. However, it is important to note that the withdrawal of EWS-FLI1 in osteosarcom
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Regarding the adverse effect of income
2018-11-14
Regarding the adverse effect of income inequality on nutritional status, Subramanian et al. (2007) suggest in their study of Indian society that income inequality can be a marker of both resource maldistribution and inefficient public policy. It is likely that unequal areas are the places where the
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The investigated functional imaging technique has great pote
2018-11-14
The investigated functional imaging technique has great potentials. Diffusion-weighted MRI may provide an aid to establish the aggressiveness of prostate cancer and help predict those tumors most likely to progress rapidly. Prostate biopsies frequently underestimate the ‘true’ Gleason score of tumor
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br Materials and Methods br Results br Discussion
2018-11-14
Materials and Methods Results Discussion Until recently, many internal organs were believed to be sterile environments. Recent studies have however changed that view, showing that even healthy placentas consistently harbor microbial communities (Aagaard et al., 2014). This study serves to s
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Histidine rich glycoprotein HRG is a kDa plasma glycoprotein
2018-11-14
Histidine-rich glycoprotein (HRG) is a 75kDa plasma glycoprotein produced in and secreted from the liver (Koide et al., 1986). The plasma levels of HRG in healthy human were reported to be constant around 1μM (Poon et al., 2011). HRG\'s primary amino cgrp sequence has an extraordinary number of hist
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VPS and SNX transport many intracellular receptors with
2018-11-14
VPS35 and SNX27 transport many intracellular receptors with broad functions. Those identified to date that regulate bone metabolism include the β1 and β2 adrenergic receptors, GPR177 — a receptor that regulates Wnt family member sorting () — and degradative RANKL transport in osteoclasts (). There a
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It is technically challenging to extract
2018-11-14
It is technically challenging to extract proteins of interest from bone due to the abundance of collagens and minerals. A pilot study using HCl/Urea extraction identified 119 proteins in OA subchondral bone with only 7 proteins shared between the low and high damage regions. This data suggests that
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br Material and Methods br Results br Discussion
2018-11-14
Material and Methods Results Discussion In this study, we show significant differences in the infectivity and cellular response between two Asian and African ZIKV strains. Using a combination of cell and molecular biology approaches, we observed in two human neural cell types (NSCs and astr
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amiodarone hcl br Materials and Methods br Results br Discus
2018-11-14
Materials and Methods Results Discussion Hypercholesterolemia is a primary risk factor for the development of atherosclerotic lesions. Despite beneficial effects of lipid-lowering statins, mortality from atherosclerosis-associated cardiovascular diseases remains high. We here investigated t
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Rupatadine Fumarate Clinical studies have demonstrated that
2018-11-14
Clinical studies have demonstrated that the ATIII activity is considerably decreased in critically ill patient with sepsis and pancreatitis (Afshari et al., 2008). Our study also found that ATIII activity was decreased in experimental model of CIN. ATIII deficiency might be caused by increased ATIII
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Asymptomatic colonization of the nasopharynx
2018-11-14
Asymptomatic colonization of the nasopharynx almost invariably precedes disease; however, pneumococci vary in their capacity to colonize the nasopharynx, both in humans and in animal models. Certain serotypes and/or clonal groups are more often isolated from carriers, while others are more often iso
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bosentan As a potential tool to further
2018-11-14
As a potential tool to further evaluate preventative vaccines the small NHP study reported here is useful and bears further evaluation. A larger study with sufficient follow-up to establish the persistence of observed viremic control is required. Also, administration of monoclonal antibody to elimin
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Developing an Artificial Bacterial Consortium to Modulate Mi
2018-11-14
Developing an Artificial Bacterial Consortium to Modulate Microbiota of Frail Elderly The microbial composition of the gut changes gradually with aging and is influenced by habitual diet and health status. In one cohort studied, frail elderly had a microbiota profile characterized by an increase in
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HIV co receptor tropism was assessed from
2018-11-14
HIV-1 co-receptor BQ-788 sodium salt was assessed from the filtered V3 MPS data using the g2p [454] tool and classified as X4 when there were more than 2% of the sequences with g2p false positivity rate (FPR) cutoffs of 3.75%, 2.5% and 1%. More detailed analysis was performed at FPR set at 2.5% to
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br Data Whole blood leukocyte distribution and plasma level
2018-11-14
Data Whole blood leukocyte distribution and plasma level of inflammatory proteins were evaluated for association with cholesterol level and CRP. Data includes correlations between leukocyte subpopulations, cholesterol and CRP in FH children and healthy children combined (Table 1, and Figs. 2 and
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