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The distorted geography on the number
2021-07-09
The distorted geography on the number lines of many pre-service primary teachers in this study also highlights the need to provide them with strong visual models of negative numbers and their ordering. The evidence from Indri's interview is that some standard models of negative numbers (e.g., lendin
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br Results br Discussion Adaptive drug resistance is a
2021-07-09
Results Discussion Adaptive drug resistance is a major challenge to the clinical success of cancer therapies. Incomplete inhibition of oncogenic signaling allows survival of “drug-tolerant” tumor cells, which persist in that state for variable periods before acquiring additional genetic mutati
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ACSF br Materials and methods br Results and discussion
2021-07-09
Materials and methods Results and discussion Conclusions Acknowledgements This work was supported financially by the LIAONING S&T Project (No. 20180550107) and Basic Scientific Research Funds of DLNU (0918110143). Introduction Since 1970s, numerous artificial mimetic enzymes have bee
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br Materials and methods br Results and discussion br
2021-07-09
Materials and methods Results and discussion Conclusions Data about the ability of non-conventional ligands to operate class-A GPCRs have been accumulating. Specifically, increasing evidence indicates that oxysterols, oxidized derivatives of cholesterol, are involved in many activities that
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In the past few years neuroprotection via GLP R
2021-07-08
In the past few years, neuroprotection via GLP-1R activation has been shown in several animal models of stroke, Alzheimer's, Parkinson's, Huntington's, ALS and traumatic SJ 172550 injury. This research field is rapidly growing and several reviews have been recently published (Darsalia et al., 2014b,
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We also observed reduced insulinotropic effects after intrav
2021-07-08
We also observed reduced insulinotropic effects after intravenous administration of both GLP-1 and GIP with atropine, whereas no inhibition was observed by atropine of the direct effects of GLP-1 and GIP action on beta-cells in the islet experiments. This suggests that the reduction in circulating i
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br Materials and methods br Results br Discussion
2021-07-08
Materials and methods Results Discussion Conflict of interest Introduction Dopamine-β-hydroxylase (DβH) deficiency is a rare autosomal recessive disorder characterized by the congenital absence of DβH, the enzyme converting dopamine to noradrenaline in sympathetic nerve terminals and
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br Enzymes repairing alkylated DNA br Induction of the Ada
2021-07-08
Enzymes repairing alkylated DNA Induction of the Ada regulon Methylated Ada is a strong activator for ada and alkA promoters. Although much weaker than the methylated form, unmethylated Ada acts alone as an activator for ada and alkA promoters. In contrast, the unmethylated protein present in
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Interest in DGKs increased as it became clear
2021-07-08
Interest in DGKs increased as it became clear that not only are they important for lipid homeostasis, they serve to modulate the relative levels of diacylglycerol (DAG) and phosphatidic Candesartan receptor (PtdOH) that play critical roles in a variety of signaling pathways (Eichmann and Lass, 2015
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br Discussion Electroporation is a convenient and efficient
2021-07-08
Discussion Electroporation is a convenient and efficient way to introduce foreign material into Fmoc-Cys(Trt)-ol [10], [16], [17], [18]. There are a lot of different protocols for transfection with electroporation. It was reported that there are several parameters that are relevant to successful
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We also determined the uracil content of
2021-07-08
We also determined the uracil content of CJ236 DNA by thin-layer chromatography of in vivo32P- or [6-3H]uracil-labeled CJ236 2′-deoxyribose 5′-monophosphates as well as by LC/MS of deoxyuridine and thymidine 2′-deoxynucleosides (Table 1, Table 2, Table 3). Examination of the 32P data showed that, b
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The positive correlation between ATG and DCTPP TCGA data
2021-07-08
The positive correlation between ATG7 and DCTPP1 (TCGA data) suggested our hypothesis that DCTPP1 may affect the phenotype of prostate tumor, or maybe other types of tumors as well, through its role in autophagy. To test this hypothesis, we carried out western-blot experiments in which the ratios of
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Steady state mRNA levels of CYP A isoforms
2021-07-08
Steady-state mRNA levels of CYP3A isoforms were not changed during liver insufficiency. Suppression of these isoforms was observed only at the protein and activity levels, suggesting a nongenomic mechanism of CYP3A isoform downregulation during liver insufficiency. Nonetheless, transcriptional activ
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Studies have shown that the cultivation
2021-07-08
Studies have shown that the cultivation of BMSCs under hypoxic conditions, treating with cytokines (such as HGF, IGF-1 and IL-6) and viral-mediated CXCR-4 gene delivery have been shown to re-establish CXCR-4 expression on the surface of stem Forskolin mg (Liu et al., 2010, Liu et al., 2014a, Ziaei
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Table shows all AP courses taken
2021-07-08
Table 5 shows all AP courses taken by participants, in descending order with respect to percentage of higher-order keywords. Table 5 also includes t-tests of mean differences for average CPA exam scores of participants who have taken (vs. not taken) AP courses (AP_ENGAGE), and average CPA exam score
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