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Eleutherococcus senticosus Rupt Maxim Maxim is a shrub belon
2020-11-19
Eleutherococcus senticosus (Rupt. & Maxim.) Maxim is a shrub belonging to the Araliaceae, which is commonly distributed in China, Korea, Japan and Russia. It has been traditionally used as folk medicine for the treatment of rheumatism, diabetes, and hepatitis (Nan et al., 2004). Recent phytochemical
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The intricate roles and neural systems and mechanisms
2020-11-19
The intricate roles and neural systems and mechanisms involved in the CRF1 and CRF2 mediation of spontaneous and stress-induced anxiety behavior remain to be defined. Of particular relevance are studies evaluating the behavioral actions of CRF1 and CRF2 receptors separately as well as together. For
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br Experimental methods br Results and discussion br
2020-11-19
Experimental methods Results and discussion Conclusions Here we describe the first reported method for high-yield bcrp inhibitor of active and soluble mature CPG2 (in the absence of the leader peptide) and its individual catalytic and dimerization domains in E. coli. Such a method is of key
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Nowadays it is possible to
2020-11-19
Nowadays it is possible to detect the AChE inhibitors by several methods such as gas chromatography-mass spectrometry [11], ion mobility spectrometry [12] and lab-on-chip devices [13,14]. However, almost all instrumental detection techniques that are able to conclusively determine the presence of th
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To date little is known about mode of action or
2020-11-19
To date, little is known about mode of action or the underlying genetic basis of DEET repellency for human-biting ticks. To begin to unveil these mechanisms, we carried out behavioral assays to confirm the effectiveness of DEET as a deterrent for D. variabilis. RNA sequencing was then used to build
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The intestinal cholesterol absorption markers sitosterol and
2020-11-19
The intestinal cholesterol Wang Resin markers sitosterol and campesterol to cholesterol levels were significantly lower in Villin-Tgif1 mice compared to wild type mice, irrespective of diet. However, the decrease was less pronounced in Villin-Tgif1 mice fed a chow diet (∼20–30%) compared to mice fed
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br Acknowledgements br Introduction Water
2020-11-19
Acknowledgements Introduction Water and electrolytes constitute an integral part of all living things, and PyBOP governing their movements play important roles in a wide variety of physiological and/or pathophysiological processes. Given the importance of channel proteins in cancer cell proli
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In patients with CTEPH ET levels are
2020-11-19
In patients with CTEPH, ET-1 levels are raised and have been shown to fall after PEA surgery [24]. After an acute pulmonary embolism there is obstruction of the pulmonary biotin-LC-LC-tyramide by acute thrombus and elevated levels of ET-1 [28], [30]. Elevated levels of ET-1 have also been observed
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Materials and Methods br Results br
2020-11-18
Materials and Methods Results Discussion For several decades, the diagnosis of translocation-associated childhood sarcomas with overlapping morphological characteristics has been facilitated by pathognomonic gene fusion detection through RT-PCR or FISH. However, these assays have several shor
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Because of the lack of sequence current knowledge on the
2020-11-18
Because of the lack of sequence, current knowledge on the cellular regulation of CoA-IT is scarce. However, recent work has suggested an interesting new role for CoA-IT in regulating the extent of the AA mobilization response in primed macrophages. Bacterial lipopolysaccharide (LPS) is a poor trigge
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br Materials and methods br Results and discussion br
2020-11-18
Materials and methods Results and discussion Concluding remarks Enzymatic production of bioactive 9-cis-11-trans-conjugated linoleic Cinobufagin mg is part of a detoxification mechanism against linoleic acid which is a toxic and stress factor for many lactic bacteria such as Lactobacillus
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In this report we describe studies of the effects
2020-11-18
In this report we describe studies of the effects of peroxisome proliferator-activated receptor γ (PPARγ) and acyl-CoA synthetase (ACSL1) on palmitate-induced ER stress in the human cardiomyocyte-like cell line AC16 [22], which was derived from adult ventricular heart tissue. PPARγ is a nuclear rece
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chronic conditions The importance of EBI for
2020-11-18
The importance of EBI2 for B cell function was first suggested by the dramatic upregulation of this receptor in EBV-transformed B cells and further inferred from its regulation in activated and GC B cells (Birkenbach et al., 1993, Glynne et al., 2000, Shaffer et al., 2000). An involvement of EBI2 in
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br Introduction The identification of genetic variants
2020-11-18
Introduction The identification of genetic variants that influence susceptibility to Parkinson's disease (PD) determines functional studies, the generation of model systems and directs therapeutic strategies. To date, classical candidate gene association studies and genome-wide approaches have fa
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Triflurdine br Introduction DNA ligation is required during
2020-11-18
Introduction DNA ligation is required during DNA replication and to complete almost all DNA repair events. In human cells, the DNA ligases encoded by three LIG genes are responsible for joining interruptions in the phosphodiester backbone [1]. These enzymes have distinct but overlapping functions
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