• gamma secretase inhibitor In the context of cataract surgery

  2019-05-13

  

  In the context of cataract surgery, Nathan Congdon and colleagues (August, p e37) propose the possibility of using early postoperative assessment of all patients or late assessment only of those who return for follow-up without additional prompting as practicable methods to improve long-term patient

• Las formas transmisibles no del saber

  2019-05-13

  

  “Las formas transmisibles, no del saber o de la sabiduría de un hombre, sino sobre todo su vida vivida —y esa es la materia con que se hacen historias— sólo son adquiridas al morir”, afirma Walter Benjamin. La muerte atraviesa toda la Historia verdadera: como motivo, como temor, como asombro o recue

• La entrega del n mero correspondiente al

  2019-05-13

  

  La entrega del número 57, correspondiente al segundo semestre de 2013, ofrece la sección Mirador Latinoamericano, donde se abordan distintos aspectos de la cultura y la literatura en nuestra América. En primer lugar, en el artículo “Crítica literaria y opinión pública: polémicas literarias en Colomb

• br Discussion Clinically HES may be separated

  2019-05-10

  

  Discussion Clinically, HES may be separated into two subgroups: HES with, and HES without gene abnormality such as PDGFRA, PDGFRB, or FGFR1. The standard therapy of HES without gene abnormality is steroid; by contrast, the first-line therapy of HES with gene abnormality is imatinib. Although in-

• orexin agonist The patient was consented to

  2019-05-10

  

  The patient was consented to treatment on clinical trial NCT02527447 and received treatment with salvage chemotherapy of mitoxantrone 12mg/m2/day IV on days 1–3, etoposide 200mg/m2/day continuous IV infusion (CIV) on days 8–10, and cytarabine 500mg/m2/day CIV on days 1–3 and 8–10 (EMA). Infectious p

• Evidence based interventions that are theory

  2019-05-10

  

  Evidence based interventions that are theory driven and accessible within the local culture are do-able and do not need to rely on imported interventions—especially when those are costly. Many bereaved children and youth reside in the NSC59984 and have little recourse to good psychosocial support,

• Prior case reports have described

  2019-05-10

  

  Prior case reports have described hematological remission in patients with myelofibrosis during treatment with bisphosphonates, but a phase II study investigating the effects of zoledronic SIRT1/2 Inhibitor IV cost on patients with myelofibrosis showed responses in only 1 of 16 patients[13]. In co

• br Discussion The excimer laser generator and the

  2019-05-09

  

  Discussion The excimer laser generator and the laser sheath allow for the extraction of leads while freeing them from the site of adhesion by making use of photoablation induced by the energy of ultraviolet rays. Since its approval in 1997 by the US Food and Drug Administration, the use of excime

• br Discussion T wave oversensing is caused by

  2019-05-09

  

  Discussion T-wave oversensing is caused by alternations or variations in intracardiac electrograms for reasons such as hyperglycemia, drugs, sympathetic tones, ventricular pacing, and hyperkalemia. Several similar cases of hyperkalemia-induced T-wave oversensing with inappropriate ICD therapies h

• In addition to inducing IKs dysfunction

  2019-05-09

  

  In addition to inducing IKs dysfunction through dominant-negative loss-of-function effects and defective channel trafficking, mutations in KCNQ1 suppress IKs channel function by reducing the channel affinity of interacting proteins [68,69]. Phosphatidylinositol-4,5-bisphosphate (PIP2) is a cofactor

• During a mean of months of follow up

  2019-05-09

  

  During a mean of 41±29 months of follow-up, freedom from VT or VF was observed more frequently in the non-inducible group (24 of 30 (75%)) than in the inducible group (9 of 21 (43%), P=0.03). The estimated cumulative freedom from VT or VF was 88%, 83%, 75%, and 55% at the 1-, 2-, 3-, and 5-year foll

• G nesis y antecedentes Juan Mar a Guti rrez nace

  2019-05-09

  

  Génesis y antecedentes Juan María Gutiérrez nace en Buenos Aires, meses previos fdps la Revolución de Mayo de 1810, donde las efemérides continentales marcan el inicio de la independencia del Río de la Plata y de casi todas las regiones dominadas por el imperio español. Es, por tanto, hijo del movi

• Social determinants are the lived conditions ie social

  2019-05-09

  

  Social determinants are the lived conditions (ie, social and economic) that influence wellbeing, and environmental influences on behaviour are those assessed with the health behaviour theory. Stages of change models (ie, those that recognise health behaviour as a series of progressive steps leading

• In addition we are continuing our regular editorial policies

  2019-05-09

  

  In addition, we are continuing our regular editorial policies of commissioning more specialised Clinical Reviews and Series across Group to provide a more focused and in-depth assessment for key diseases. And beyond providing knowledge and information, we want to encourage academic and practising c

• br Methods br Results In patients we

  2019-05-09

  

  Methods Results In 22 patients, we analyzed 82 sites at which HFS was delivered. We identified 57 GP-positive sites on the basis of a vagal response (19 at the MTGP, 18 at the SLGP, and 20 at the ARGP) and 25 GP-negative sites. After delivery of radiofrequency glucokinase inhibitor (30–35W fo

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