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MCMSim was developed using Blender v a popular and free
2018-11-15
MCMSim was developed using Blender (v2.49), a popular and free open source 3D modelling and animation tool and game engine. Blender\'s interface simultaneously supports concurrent 3D modelling and simulation/game development and, as such, suits the rapid development and evaluation of proof-of-concep
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br Study area We selected the Qiaobei development district o
2018-11-14
Study area We selected the Qiaobei development district of Nanjing as our study area because it is representative of the urban growth pattern that can be observed in most large Chinese cities (Figure 3). The Qiaobei development district is located at the fringe of Nanjing’s metropolitan area. The
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congo red Instead of wide excision with reconstruction
2018-11-14
Instead of wide excision with reconstruction, in this case we designed an intralesional tumor excision to preserve the structures adjacent to the hip joint. To reduce local recurrence, phenol was used to cauterize the tumor margin and the defect was filled with cisplatin-loaded cement. Schiller and
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The week in vitro culture protocol
2018-11-14
The 15week in vitro culture protocol used in this study provided a very challenging culture system to examine long term potential of the cell sources. When grown in a large 6mm×9mm PCL scaffold, the AFS casein kinase had great potential but the cells required an extensive induction time prior to th
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Recently we and others demonstrated
2018-11-14
Recently, we and others demonstrated that cells with astroglial characteristics and radial processes are still present in specific regions of the adult brain. These cells are termed radial glia-like cells (RGLCs) and they are present in the SVZ and in the SGL (Alvarez-Buylla et al., 2002; Gubert et
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The fact that the in vitro induction
2018-11-14
The fact that the in vitro induction of osteogenic differentiation leads to sarcoma development from sarcoma iPSCs in concert with EWS-FLI1 expression indicates that these sarcomas arise from osteogenic progenitor cells. However, it is important to note that the withdrawal of EWS-FLI1 in osteosarcom
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Regarding the adverse effect of income
2018-11-14
Regarding the adverse effect of income inequality on nutritional status, Subramanian et al. (2007) suggest in their study of Indian society that income inequality can be a marker of both resource maldistribution and inefficient public policy. It is likely that unequal areas are the places where the
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The investigated functional imaging technique has great pote
2018-11-14
The investigated functional imaging technique has great potentials. Diffusion-weighted MRI may provide an aid to establish the aggressiveness of prostate cancer and help predict those tumors most likely to progress rapidly. Prostate biopsies frequently underestimate the ‘true’ Gleason score of tumor
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br Materials and Methods br Results br Discussion
2018-11-14
Materials and Methods Results Discussion Until recently, many internal organs were believed to be sterile environments. Recent studies have however changed that view, showing that even healthy placentas consistently harbor microbial communities (Aagaard et al., 2014). This study serves to s
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Histidine rich glycoprotein HRG is a kDa plasma glycoprotein
2018-11-14
Histidine-rich glycoprotein (HRG) is a 75kDa plasma glycoprotein produced in and secreted from the liver (Koide et al., 1986). The plasma levels of HRG in healthy human were reported to be constant around 1μM (Poon et al., 2011). HRG\'s primary amino cgrp sequence has an extraordinary number of hist
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VPS and SNX transport many intracellular receptors with
2018-11-14
VPS35 and SNX27 transport many intracellular receptors with broad functions. Those identified to date that regulate bone metabolism include the β1 and β2 adrenergic receptors, GPR177 — a receptor that regulates Wnt family member sorting () — and degradative RANKL transport in osteoclasts (). There a
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It is technically challenging to extract
2018-11-14
It is technically challenging to extract proteins of interest from bone due to the abundance of collagens and minerals. A pilot study using HCl/Urea extraction identified 119 proteins in OA subchondral bone with only 7 proteins shared between the low and high damage regions. This data suggests that
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br Material and Methods br Results br Discussion
2018-11-14
Material and Methods Results Discussion In this study, we show significant differences in the infectivity and cellular response between two Asian and African ZIKV strains. Using a combination of cell and molecular biology approaches, we observed in two human neural cell types (NSCs and astr
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amiodarone hcl br Materials and Methods br Results br Discus
2018-11-14
Materials and Methods Results Discussion Hypercholesterolemia is a primary risk factor for the development of atherosclerotic lesions. Despite beneficial effects of lipid-lowering statins, mortality from atherosclerosis-associated cardiovascular diseases remains high. We here investigated t
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Rupatadine Fumarate Clinical studies have demonstrated that
2018-11-14
Clinical studies have demonstrated that the ATIII activity is considerably decreased in critically ill patient with sepsis and pancreatitis (Afshari et al., 2008). Our study also found that ATIII activity was decreased in experimental model of CIN. ATIII deficiency might be caused by increased ATIII
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